Peptide Database

Peptide NameBrevinin-2GRc

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC87H149N27O29S3

DescriptionStandard

        AKEAGKTGHELMACKITNQC
    

Molecular Weight2133.47 Da

Isoelectric Point (pI)8.08

Net Charge (pH 7.0)0.87

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0433

GRAVY Index-0.53

Hydrophobic Moment 0.56

Boman Index-0.08

Instability Index9.85

Aliphatic Index 54.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 924.20

LogP -11.38

H-bond Donors 33.0

H-bond Acceptors 34.0

Rotatable Bonds 75.0

Heavy Atoms 146.0

Ring Count 1.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0189098 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana grahami [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)