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MYP_095041
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Basic Information
Unnamed
Antimicrobial
Antiviral
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Delivery / Targeting ▸ Drug delivery vehicle ▸ Drug delivery
Delivery / Targeting ▸ Targeting ligand ▸ Targeting
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Standard
2 amino acids
C14H18N2O3
Standard
Sequence
FP
Physicochemical Analysis
262.30 Da
5.53
-0.24
-0.44
-0.1200
0.60
0.59
0.66
101.30
0.00
0.5000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
83.63
0.63
2.0
3.0
4.0
19.0
2.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0192264 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
ACE-inhibitory peptide
9925
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
315 μM
IC50
PaperPreparation of angiotensin-I-converting enzyme inhibitory hydrolysates from unsupplemented caprine whey fermentation by various cheese microflora PMID9891260 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9891260/
RECORD: Rec_0202540 VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
PaperAngiotensin-converting enzyme-inhibitory peptides in Manchego cheeses manufactured with different starter cultures
RECORD: Rec_0207331 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Serum albumin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
205 μM
IC50
PaperCharacterization of New Milk-derived Inhibitors of Angiotensin Converting Enzyme In Vitro and In Vivo | Fuglsang, A. et al. | DOI: 10.1080/1475636031000138723 Evidence URLhttps://www.uniprot.org/uniprotkb/P02769/entry
RECORD: Rec_0219945 VERIFIED: NO
Provenance & Taxonomy
Amaranthus hypochondriacus [Plant]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperBioactive peptides in amaranth (Amaranthus hypochondriacus) seed PMID18211015 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18211015/
RECORD: Rec_0237848 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: fosfamide; Conjugated small molecule: AZT monophosphate
Bio-Activity Profile
Antimicrobial Antiviral Drug delivery Targeting
HIV
PaperAZT and AZT-monophosphate prodrugs incorporating HIV-protease substrate fragment: synthesis and evaluation as specific drug delivery systems PMID17066898 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17066898/
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