Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC424H670N116O127S13

DescriptionStandard

        MKTFSVAVAVAVVLTFICVQQSSAVPVTEQEQELEEPMSMDYPAAAHEEASVDSWKMLYNSRHKRGIKCRFCCGCCTPGICGVCCRFNL
    

Molecular Weight9841.40 Da

Isoelectric Point (pI)6.05

Net Charge (pH 7.0)-1.40

Net Charge (pH 7.4) -1.87

Charge Density (pH 7.0) -0.0157

GRAVY Index0.16

Hydrophobic Moment 0.45

Boman Index0.08

Instability Index66.09

Aliphatic Index 72.25

Aromaticity 0.0787

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3871.02

LogP -39.59

H-bond Donors 142.0

H-bond Acceptors 141.0

Rotatable Bonds 320.0

Heavy Atoms 680.0

Ring Count 14.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0181379 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus [Animal]

FamilyHepcidin

Tax ID8128

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal