Peptide Database

Peptide NameCRS4C-6 (cDNA sequence AY761185)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC436H698N116O145S12

DescriptionStandard

        MKTLVLLSALVLLAFYVQADSTQETDEETKTDDQPGEEDQGVSVSFEDPERYVLQVSGLGKPPQCPKCPVCSKCPQCPQCPQCPGCPRCNCMTK
    

Molecular Weight10269.68 Da

Isoelectric Point (pI)4.50

Net Charge (pH 7.0)-5.58

Net Charge (pH 7.4) -5.97

Charge Density (pH 7.0) -0.0594

GRAVY Index-0.43

Hydrophobic Moment 0.60

Boman Index-0.05

Instability Index55.52

Aliphatic Index 61.06

Aromaticity 0.0426

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4151.87

LogP -48.22

H-bond Donors 143.0

H-bond Acceptors 152.0

Rotatable Bonds 330.0

Heavy Atoms 709.0

Ring Count 15.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0313669 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic