Peptide Database

Peptide NameConotoxin Lt5.3

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC60H87N15O16S5

DescriptionStandard

        DCCPAKMFCCQW
    

Molecular Weight1434.75 Da

Isoelectric Point (pI)5.81

Net Charge (pH 7.0)-0.28

Net Charge (pH 7.4) -0.54

Charge Density (pH 7.0) -0.0233

GRAVY Index0.26

Hydrophobic Moment 0.23

Boman Index0.11

Instability Index62.15

Aliphatic Index 8.33

Aromaticity 0.1667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 496.83

LogP -3.43

H-bond Donors 20.0

H-bond Acceptors 21.0

Rotatable Bonds 42.0

Heavy Atoms 96.0

Ring Count 4.0

Amide Bonds 12.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0152954 VERIFIED: NO

Provenance & Taxonomy

OrganismConus litteratus [Animal]

FamilyConotoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0394576 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic