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MYP_094829
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Basic Information
Trialysin (1-33)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
32 amino acids
C167H293N43O37
Standard
Sequence
FKIKPGKVLDKFGKIVGKVLKQLKKVSAVAKV
Physicochemical Analysis
3495.38 Da
10.60
8.75
8.53
0.2735
0.16
0.77
0.02
-29.77
121.56
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1317.45
-6.46
45.0
46.0
128.0
247.0
3.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0023981 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Trypanosoma cruzi Y
1.4 μg/mL
LC50
PMID16460023 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16460023/
RECORD: Rec_0251112 VERIFIED: YES
Provenance & Taxonomy
Triatoma infestans [Animal]
Trialysin
30076
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Cytolytic Antiparasitic Anti-Trypanosoma cruzi
Trypanosoma cruzi
0.4 μM
LC50; Microscopy (Surviving parasites counted by Neubauer hemocytometer)
PMID16460023 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16460023/
RECORD: Rec_0257553 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
316 μg/mL
Hemolysis
PMID16460023 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16460023/
RECORD: Rec_0273339 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Hemolytic
Human erythrocytes
90 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/16460023/ PMID16460023 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16460023/
RECORD: Rec_0391463 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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