Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length179 amino acids

Chemical FormulaC854H1334N242O273S15

DescriptionStandard

        NVEQTNKDKKFLIPTAENFLHSPSQHPSESDASLKSHYCTVGAVSDEATAALVSINSSRFYTFNHQTGEEVKGADKSHQKSERIETLKQSNPPKMKTFSVAVAVAVVLAFICLQESSAVPVTEVQELEEPMSNEYQEMPVESWKMPYNNRHKRHSSPGGCRFCCSCCPNMSGCGVCCRF
    

Molecular Weight19840.16 Da

Isoelectric Point (pI)6.41

Net Charge (pH 7.0)-1.70

Net Charge (pH 7.4) -2.45

Charge Density (pH 7.0) -0.0095

GRAVY Index-0.50

Hydrophobic Moment 0.54

Boman Index-0.06

Instability Index73.58

Aliphatic Index 57.15

Aromaticity 0.0726

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 12085.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8276.29

LogP -101.27

H-bond Donors 290.0

H-bond Acceptors 293.0

Rotatable Bonds 653.0

Heavy Atoms 1384.0

Ring Count 32.0

Amide Bonds 196.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0138556 VERIFIED: NO

Provenance & Taxonomy

OrganismDicentrarchus labrax [Animal]

FamilyHepcidin

Tax ID13489

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal