Peptide Database

Peptide NameDefb14-1CV (1-23)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC100H182N38O31S

DescriptionStandard

        LGKEEQIGRASNSGRKCARKKK
    

Molecular Weight2444.82 Da

Isoelectric Point (pI)10.56

Net Charge (pH 7.0)5.75

Net Charge (pH 7.4) 5.52

Charge Density (pH 7.0) 0.2614

GRAVY Index-1.61

Hydrophobic Moment 0.76

Boman Index-0.60

Instability Index29.26

Aliphatic Index 44.55

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1191.46

LogP -16.18

H-bond Donors 44.0

H-bond Acceptors 38.0

Rotatable Bonds 93.0

Heavy Atoms 170.0

Ring Count 0.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0229265 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMonomer: [Pseudomonas aeruginosa PAO1

Activity20.5 μM

MethodMIC

RECORD: Rec_0331240 VERIFIED: YES