Peptide Database

Peptide NameInterferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (GBP-2) (mGBP-2) (mGBP2) (Guanine nucleotide-binding protein 2)

Function Ontology

Antimicrobial

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Antiviral

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length589 amino acids

Chemical FormulaC2962H4749N783O913S25

DescriptionStandard

        MASEIHMSEPMCLIENTEAQLVINQEALRILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKRTGFSLGSTVQSHTKGIWMWCVPHPKKAGQTLVLLDTEGLEDVEKGDNQNDCWIFALAVLLSSTFIYNSIGTINQQAMDQLHYVTELTDLIKSKSSPDQSGVDDSANFVGFFPTFVWTLRDFSLELEVNGKPVTSDEYLEHSLTLKKGADKKTKSFNEPRLCIRKFFPKRKCFIFDRPAQRKQLSKLETLREEELCGEFVEQVAEFTSYILSYSSVKTLCGGIIVNGPRLKSLVQTYVGAISNGSLPCMESAVLTLAQIENSAAVQKAITHYEEQMNQKIQMPTETLQELLDLHRPIESEAIEVFLKNSFKDVDQKFQTELGNLLVAKRDAFIKKNMDVSSARCSDLLEDIFGPLEEEVKLGTFSKPGGYYLFLQMRQELEKKYNQAPGKGLQAEAMLKNYFDSKADVVETLLQTDQSLTEAAKEVEEERTKAEAAEAANRELEKKQKEFELMMQQKEKSYQEHVKKLTEKMKDEQKQLLAEQENIIAAKLREQEKFLKEGFENESKKLIREIDTLKQNKSSGKCTIL
    

Molecular Weight66738.72 Da

Isoelectric Point (pI)5.56

Net Charge (pH 7.0)-10.77

Net Charge (pH 7.4) -11.76

Charge Density (pH 7.0) -0.0183

GRAVY Index-0.41

Hydrophobic Moment 0.73

Boman Index-0.04

Instability Index41.05

Aliphatic Index 86.76

Aromaticity 0.0747

Extinction Coeff. Reduced 42860.00

Extinction Coeff. Oxidized 43485.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0139447 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

Tax ID10090

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

RECORD: Rec_0321256 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyTRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antiprotozoal Hydrolase Non-hemolytic

TargetToxoplasma gondii