Peptide Database

Peptide NameProgonadoliberin-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC338H532N100O102S3

DescriptionStandard

        QHWSYGLRPGGKRDTESLQDMYHETPNEVALFPELERLECSVPQSRLNVLRGALMNWLEGENRKKI
    

Molecular Weight7724.64 Da

Isoelectric Point (pI)6.11

Net Charge (pH 7.0)-1.06

Net Charge (pH 7.4) -1.40

Charge Density (pH 7.0) -0.0160

GRAVY Index-0.88

Hydrophobic Moment 0.52

Boman Index-0.17

Instability Index62.20

Aliphatic Index 75.30

Aromaticity 0.0758

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3294.53

LogP -31.62

H-bond Donors 114.0

H-bond Acceptors 106.0

Rotatable Bonds 258.0

Heavy Atoms 543.0

Ring Count 13.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0333445 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

FamilyProgonadoliberin

Tax ID8355

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour