Peptide Database

Peptide NameUncharacterized protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length612 amino acids

Chemical FormulaC3008H4881N865O902S14

DescriptionStandard

        MLSAYTVILCAFYLMKEENAMSEGDRKGHDRDMQTIGSVDSKGGDGEVLANHDTMTVTSDRKSDRGWGGGSGNSGDHERIDRTGKNEGVNLSLFPEAQASAAIGAQPMNISVIDGLWGFTLLRKQIASAVSSTLTRLGSVALDAAPYVGRFAGVAVGAMWPSDLKIPEDEKFKAERQRMIIQAIQASQVTKTPVSQLATMSSVVTDIQVQDVIERDKQTLAIVRTPAKTVSVPVVKAVKTKRQNVFTAKVVPNMPSVHIRISDPSRRKIFGRREVTPIADVPIKPYTPAPVKNTVDAIVHFPVGSNAEPVYVSVTTVLSSAEAKKQAAEAKQQQEKWEKAHPVEAAERRLYEAEQVFKPLDKIYQEKLKILNQVKNTPEGKALADPVKNPLVFIKDIEIDGKKLKVEIKTDNKKGLDILLKEGVKAYMLAMTRSDFEKLQSIKDPKEAPLQTSAAFLKAIYYERFGRRLLDAWKKINPAQNEFNIAMENRKKAEQAKSEAEKNRDKVKEENRKERKGVKEAGHDYYPAPKTEEIKGLGELKRGPQKTPKQNGGGKRKRWIGEKGRRIYEWDSQHGELEGYRVSDGQHIGVFDHKTGKQLAAADPKRSIKKFL
    

Molecular Weight68044.10 Da

Isoelectric Point (pI)9.57

Net Charge (pH 7.0)24.45

Net Charge (pH 7.4) 23.49

Charge Density (pH 7.0) 0.0399

GRAVY Index-0.61

Hydrophobic Moment 0.93

Boman Index-0.12

Instability Index39.54

Aliphatic Index 78.58

Aromaticity 0.0605

Extinction Coeff. Reduced 59360.00

Extinction Coeff. Oxidized 59360.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0269633 VERIFIED: NO

Provenance & Taxonomy

OrganismPhotorhabdus khanii subsp. guanajuatensis [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence

PaperPhotorhabdus khanii subsp. guanajuatensis subsp. nov., isolated from Heterorhabditis atacamensis, and Photorhabdus luminescens subsp. mexicana subsp. nov., isolated from Heterorhabditis mexicana entomopathogenic nematodes PMID30688647 Evidence URLhttps://www.uniprot.org/uniprotkb/A0A4R4JQ85/entry