Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC414H657N105O124S13

DescriptionStandard

        MKTFSVAVAVAIVLTFICIQQSSAVPTAEVQEVEEPMSVEFPLAEQEETSVDSWMMPYNIREKRGIKCKFCCGCCTPGVCGLCCRF
    

Molecular Weight9506.12 Da

Isoelectric Point (pI)4.80

Net Charge (pH 7.0)-3.57

Net Charge (pH 7.4) -3.94

Charge Density (pH 7.0) -0.0415

GRAVY Index0.34

Hydrophobic Moment 0.38

Boman Index0.15

Instability Index64.35

Aliphatic Index 76.98

Aromaticity 0.0814

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3629.65

LogP -33.66

H-bond Donors 132.0

H-bond Acceptors 134.0

Rotatable Bonds 309.0

Heavy Atoms 656.0

Ring Count 13.0

Amide Bonds 90.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0358301 VERIFIED: NO

Provenance & Taxonomy

OrganismGasterosteus aculeatus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence