Peptide Database

Peptide NamePENK 114-133

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC61H97N15O26

DescriptionStandard

        VEPEEEANGGEILA
    

Molecular Weight1456.51 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-5.25

Net Charge (pH 7.4) -5.47

Charge Density (pH 7.0) -0.3751

GRAVY Index-0.52

Hydrophobic Moment 0.21

Boman Index0.10

Instability Index102.24

Aliphatic Index 90.71

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 662.42

LogP -6.54

H-bond Donors 20.0

H-bond Acceptors 21.0

Rotatable Bonds 48.0

Heavy Atoms 102.0

Ring Count 1.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326926 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyPENK

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Analgesic Pronociceptive Neuropeptide Neuromodulator Growth regulation Development regulation Receptor modulation

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0426876 VERIFIED: YES