Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length677 amino acids

Chemical FormulaC3069H4906N922O992S16

DescriptionStandard

        MSGNGGDNAHDSAFGGGRNPGMGNSGSEDHSGSSGNSGSGSQSGAGHFTGPSTTIGPDGQVHINLEGWSEDKGKPGSNGGKGGSGKGEGGQIQGALLTPVPGKPGSYTSSNPGQTMLATSIDDNSENGTGSYTLHTGKNQTIEVTVPNGDIKQMTVEYNNWKGPKLKYKDMQKFISAFMDATAPDRARREEARRAEETRKAEEARKAEEARKAEEARKAEETRKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAADVAKGEAARKALFASVGILNAPSYTPEMVRAANAALSGEGAMALGRAPGMIQFSGAGTLPFSPGVAGGEAGAIWRGVTELSRIATATPQGAVIAATIFSIFHIPSAGEGSDRVPDRDIDMLAAQASLYTAMKTEITPGMKTADLPVRGYISGDGNGRQSVNLVRTGTGGISPTVPVLNAVRDKATGLDRITVPAVGGAPARTILVNPVPVGPNATWHTGNDAPVPMTPVHTGTEVKQADSIVTTTFPAGDIPPLQDFIYWQPDATGTGVEPIYVMLSSPRDLPGKASGKGEKVGEGWLNIAGQELGAPIPSQIADKLRGREFANFGSFRRAFWTEVSKDPELSKQFDPGSIATMKNGRAAYVRKTERIGKRVKMELHHIKPINENGAVYDADNLGVVTPKRHIEIHSNKGSNRNG
    

Molecular Weight71104.41 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)2.67

Net Charge (pH 7.4) 1.66

Charge Density (pH 7.0) 0.0039

GRAVY Index-0.60

Hydrophobic Moment 0.93

Boman Index-0.05

Instability Index36.03

Aliphatic Index 63.10

Aromaticity 0.0502

Extinction Coeff. Reduced 54890.00

Extinction Coeff. Oxidized 54890.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0336805 VERIFIED: NO

Provenance & Taxonomy

OrganismPluralibacter gergoviae [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence