Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length445 amino acids

Chemical FormulaC2214H3500N578O621S19

DescriptionStandard

        MARGPCNAPRWASLLVLVVVGTAVAAAINPGVVVRISQKGLDYATQQGTAALQKELERIKIPDYSGSFKIKLLGKGHYSFYRKTSGGFDLSIGGTSISADLMLGSNLTSGKPTVTCASCSSHISSVHVHISNSKVGWLIQLFHKKIESALRNKLNSQVCQKLTSSVSSELQPYFQTLPVMTKIDAVAGIDYGLVAPPTITAETLDAQMKGEFYRLNHHNPPPFAPPVMEFPAAHDRMVYLGLSDYFFNTAGLVYQEAGVLKMTLTDDMIPKESRFRLTTKFFGSFLPEVAKMFPNMKMQIHISASVPPQLSVQPTGLSFFPALDIQAFAVLANSSLASLFLIGMSTHGSLEVSARSDRLVGELNVDRLLLELKHSTIGPFPVELLQDIMNYIVPTLVLPRVNVVSITERLQKGFPLPMPARVQFYNMVLQPHQNFLLFGADVVYK
    

Molecular Weight48760.21 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)8.53

Net Charge (pH 7.4) 7.56

Charge Density (pH 7.0) 0.0192

GRAVY Index0.14

Hydrophobic Moment 0.70

Boman Index0.15

Instability Index40.41

Aliphatic Index 97.91

Aromaticity 0.0876

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0341389 VERIFIED: NO

Provenance & Taxonomy

OrganismSapajus apella (Brown-capped capuchin) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria