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MYP_094517
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Basic Information
Ponericin-L2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C123H217N31O28
Standard
Sequence
LLKELWTKIKGAGKAVLGKIKGLL
Physicochemical Analysis
2578.23 Da
10.30
4.76
4.54
0.1982
0.40
0.50
0.18
-22.19
150.42
0.0417
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
962.06
-3.12
34.0
33.0
94.0
182.0
2.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0304900 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterobacter cloacae CIP 6085
PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0317569 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral Hemolytic
PaperPonericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii. J Biol Chem. 2001 May 25;276(21):17823-9. doi: 10.1074/jbc.M100216200. PMID: 11279030. PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0320520 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral
Lactococcus lactis ssp
PaperPonericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii. J Biol Chem. 2001 May 25;276(21):17823-9. doi: 10.1074/jbc.M100216200. PMID: 11279030. PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0327096 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
E. coliL
PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0327400 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 58.3%, E 0.0%, T 29.2%, C 12.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antiviral Antimicrobial Anti-Gram-positive Anti-Gram-negative Insecticidal
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
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