Peptide Database

Peptide NameTumor necrosis factor, soluble form

Function Ontology

Anticancer ▸ tumor necrosis factor family

Antimicrobial ▸ Antibacterial

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length156 amino acids

Chemical FormulaC781H1210N200O235S3

DescriptionStandard

        LRSSSQNSSDKPVAHVVANHQVEEQLEWLSQRANALLANGMDLKDNQLVVPADGLYLVYSQVLFKGQGCPDYVLLTHTVSRFAISYQEKVNLLSAVKSPCPKDTPEGAELKPWYEPIYLGGVFQLEKGDQLSAEVNLPKYLDFAESGQVYFGVIAL
    

Molecular Weight17257.36 Da

Isoelectric Point (pI)4.96

Net Charge (pH 7.0)-5.98

Net Charge (pH 7.4) -6.41

Charge Density (pH 7.0) -0.0383

GRAVY Index-0.16

Hydrophobic Moment 0.43

Boman Index0.09

Instability Index27.17

Aliphatic Index 97.44

Aromaticity 0.0962

Extinction Coeff. Reduced 22920.00

Extinction Coeff. Oxidized 23045.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6964.75

LogP -63.50

H-bond Donors 233.0

H-bond Acceptors 235.0

Rotatable Bonds 564.0

Heavy Atoms 1219.0

Ring Count 29.0

Amide Bonds 173.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0037352 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

Familytumor necrosis factor family

Tax ID10090; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide69-100

Bio-Activity Profile

Function

Cytokine Growth factor tumor necrosis factor family Antibacterial Chemokine-like Host defense