Peptide Database

Peptide NameCompond 5 (ABT-526)

Function Ontology

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC41H77N15O12

DescriptionStandard

        SARGVITIR
    

Molecular Weight972.14 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)1.46

Net Charge (pH 7.4) 1.25

Charge Density (pH 7.0) 0.1622

GRAVY Index0.46

Hydrophobic Moment 0.33

Boman Index-0.04

Instability Index-0.54

Aliphatic Index 130.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 460.38

LogP -5.42

H-bond Donors 18.0

H-bond Acceptors 14.0

Rotatable Bonds 32.0

Heavy Atoms 68.0

Ring Count 0.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0299822 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermAcetylation

C-TermN-Ethylmaleimidation

Other ModsSar- Sarcosine

Bio-Activity Profile

Function

Anti-angiogenic

Activity3e-05±1.5e-05 μM

MethodIC50

Half-LifeMouse plamsa, in vivo; 4320 s