Peptide Database

Peptide NameCecropin A (1-8)+Lactoferricin B15(W4,10)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC158H232N42O25S

DescriptionStandard

        KWKLFKKIFKCWRWQWRWKKLGA
    

Molecular Weight3151.86 Da

Isoelectric Point (pI)11.30

Net Charge (pH 7.0)8.74

Net Charge (pH 7.4) 8.52

Charge Density (pH 7.0) 0.3801

GRAVY Index-0.99

Hydrophobic Moment 0.90

Boman Index-0.22

Instability Index41.83

Aliphatic Index 55.22

Aromaticity 0.3043

Extinction Coeff. Reduced 27500.00

Extinction Coeff. Oxidized 27500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1131.50

LogP 0.58

H-bond Donors 44.0

H-bond Acceptors 35.0

Rotatable Bonds 105.0

Heavy Atoms 226.0

Ring Count 12.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0190984 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans CGMCC 2.2411

Activity100 μM

MethodIC50

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