Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length485 amino acids

Chemical FormulaC2482H3844N652O700S16

DescriptionStandard

        MMARPYYMVVALLLLAEFTRFGEGTPNPGFMVRITGKGLEYARQYGVATLKNDLSTIKLPDLSGSYGIGWLGSVNYVFSGMRIHHFLLRNSQLSLHPRQGIKASLSNNHVSVSGNWKVKKSFITLHGTFDLSVDGMSILVSLNLDKDQSGRPTVSVTHCHNSIGHVSIEISGHISWILNLFHERIENNVKNILEQKICKMVKESAASRLEPYLRTLPVTSMIDQIAGIDYRLVGAPQVTFQGLDTPFKGEFFGRNWNSSVPFDAPPITLPQKNDHMIYFAVSEYVFNTASRVYHQAGQMKFTIQNKHIPLDFPIQLHTSSFWAIIPQLARLYPNMELELETSPESAPFLTFTPGNVTFMPVMDIQAFVLDEDLWPKSAGRKPLFQIRASTNISITINVNSSRITGSLTTGSELKLELKHSNIGFFNVNLMESIFNYYALHIVYPSLNAKLEEGIPLPLPRDTYLNSLEFQIHKNFVFLGANVDVD
    

Molecular Weight54530.06 Da

Isoelectric Point (pI)7.83

Net Charge (pH 7.0)2.01

Net Charge (pH 7.4) 0.80

Charge Density (pH 7.0) 0.0041

GRAVY Index-0.05

Hydrophobic Moment 0.71

Boman Index0.12

Instability Index36.92

Aliphatic Index 94.64

Aromaticity 0.1052

Extinction Coeff. Reduced 56840.00

Extinction Coeff. Oxidized 56965.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0265360 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria