Peptide Database

Peptide NameEnzyme inhibitor 18

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC36H55N7O9

DescriptionStandard

        IPLQPY
    

Molecular Weight729.86 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0401

GRAVY Index0.05

Hydrophobic Moment 0.13

Boman Index0.35

Instability Index89.97

Aliphatic Index 130.00

Aromaticity 0.1667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 254.56

LogP 0.14

H-bond Donors 7.0

H-bond Acceptors 9.0

Rotatable Bonds 18.0

Heavy Atoms 52.0

Ring Count 3.0

Amide Bonds 6.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0198852 VERIFIED: YES

Provenance & Taxonomy

OrganismHordeum vulgare [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory DPP-IV inhibitory

TargetDipeptidyl peptidase IV

Activity3.10±0.60 μM

MethodIC50

RECORD: Rec_0322634 VERIFIED: YES