Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length517 amino acids

Chemical FormulaC2638H4072N664O751S22

DescriptionStandard

        MCTKMAQVQVQVLWGCFILWNLYISSAQAIYPGIKARATRRALDYAVQAGMEMIEQMAKERKLPDLKGSESLEFLKIDYVNYNFTNIKITAFSFPNTSLSFVPGVGIRALTNHGTTNISTDWDVKSPLFQDTGAADLFLSGVYFTGIVVLSRNDFGHPILKLQDCYAQVSHADVSFSGELSVLYNSFAEPMEKPILKKLNEMLCPIITGEVEALNANLSKLEVLRKMDNYTLLDYSLVSPPEITENYFDLNLKGVFYPLKSLQYPPFPSVPFVLPERSDSMLYIGISKYFFKSASYAYFTAGAFSFTLTTKEISNHLLHNSQALGNMLSRIAELYILSQPFMVQVMATEPPVIRLLPGNFTLDIPASIMILTQPKNSTAETIVSMDFVASTNVALAILGQRLIYWETNRGEKLSPQFYQVFKGLISPLNSIGMVPRAYETSETHENLPEVHKSALTLQTGFPGGTSSKKPSCPNAGDMRCWFEPWVGKIAWRRTWQPTPVFLPGESHGQRSLAGYNP
    

Molecular Weight57809.98 Da

Isoelectric Point (pI)6.72

Net Charge (pH 7.0)-0.81

Net Charge (pH 7.4) -1.65

Charge Density (pH 7.0) -0.0016

GRAVY Index-0.02

Hydrophobic Moment 0.76

Boman Index0.13

Instability Index38.42

Aliphatic Index 89.79

Aromaticity 0.1141

Extinction Coeff. Reduced 76780.00

Extinction Coeff. Oxidized 77155.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0142472 VERIFIED: NO

Provenance & Taxonomy

OrganismMuntiacus muntjak [Animal]

FamilyBPI

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence