Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC72H114N16O26S

DescriptionStandard

        ILMAFSIDSPDSLEN
    

Molecular Weight1651.83 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.23

Net Charge (pH 7.4) -3.44

Charge Density (pH 7.0) -0.2157

GRAVY Index0.34

Hydrophobic Moment 0.25

Boman Index0.24

Instability Index80.35

Aliphatic Index 110.67

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 677.61

LogP -6.44

H-bond Donors 22.0

H-bond Acceptors 24.0

Rotatable Bonds 53.0

Heavy Atoms 115.0

Ring Count 2.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124047 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0141040 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyRhoA-derived

Tax ID9606;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor

TargetRespiratory syncytial virus (Virus entry); HEp2

Activity60.538232 μM

MethodFlow cytometry

PaperRhoA-derived peptide dimers share mechanistic properties with other polyanionic inhibitors of respiratory syncytial virus (RSV), including disruption of viral attachment and dependence on RSV G. | Budge PJ, Li Y, Beeler JA, Graham BS. | J Virol. 2004 | PMID:15113882 PMID15113882 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113882/