Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC746H1165N235O219S6

DescriptionStandard

        MSRVQFKQREATNAIFVHCSATKATQDVGVREIRQWHKEQGWLDVGYHFIIRRDGTVEDGRDVNAVGSHARGHNHNSVGVCLVGGIDERGRHEANFTPQQMSALRTLLEVLMDKYPSAVLKAHHDVAPKACPSFDLQRWWKHNELVTSDRG
    

Molecular Weight17122.06 Da

Isoelectric Point (pI)8.53

Net Charge (pH 7.0)2.37

Net Charge (pH 7.4) 1.57

Charge Density (pH 7.0) 0.0157

GRAVY Index-0.60

Hydrophobic Moment 0.75

Boman Index-0.11

Instability Index48.25

Aliphatic Index 72.91

Aromaticity 0.0728

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7348.53

LogP -78.87

H-bond Donors 260.0

H-bond Acceptors 237.0

Rotatable Bonds 569.0

Heavy Atoms 1206.0

Ring Count 29.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0117607 VERIFIED: NO

Provenance & Taxonomy

OrganismAeromonas phage PZL-Ah1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic