Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length53 amino acids

Chemical FormulaC256H395N69O84S5

DescriptionStandard

        MDKLNHSAVTSLNEVSDSELDTILGGSRFWQGVVPTVSYECRMNSWQSIFTCC
    

Molecular Weight5943.61 Da

Isoelectric Point (pI)4.58

Net Charge (pH 7.0)-3.43

Net Charge (pH 7.4) -3.75

Charge Density (pH 7.0) -0.0648

GRAVY Index-0.11

Hydrophobic Moment 0.56

Boman Index0.06

Instability Index37.83

Aliphatic Index 73.40

Aromaticity 0.0943

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2480.05

LogP -28.98

H-bond Donors 90.0

H-bond Acceptors 87.0

Rotatable Bonds 193.0

Heavy Atoms 414.0

Ring Count 9.0

Amide Bonds 57.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008828 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus gallolyticus [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria