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MYP_094103
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Basic Information
Dermaseptin-AC4 [A10L,A12K,A17V,L18A,V25A], DRP-AC4a
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
27 amino acids
C123H208N36O35S
Standard
Sequence
SLWGKLKEMLAKAGKAVANAVNGLANQ
Physicochemical Analysis
2783.25 Da
10.00
2.46
2.24
0.0911
0.01
0.60
0.11
-6.38
101.48
0.0370
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1169.68
-11.74
39.0
39.0
97.0
195.0
2.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0284736 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
8 μM
MIC
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
RECORD: Rec_0334642 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
16 μM
MBC
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
RECORD: Rec_0384473 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse erythrocytes
10 % Hemolysis
Hemolysis
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
RECORD: Rec_0386536 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 12493
8 μM
MIC
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
RECORD: Rec_0406161 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae ATCC 43816
16 μM
MBC
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
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