Peptide Database

Peptide NameNeutrophil beta defensin 11

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length54 amino acids

Chemical FormulaC266H428N80O61S7

DescriptionStandard

        LLALLFLVLFAGSGISGPLSCHRKRGVCFPIRCPGHMRQIGTCFGRPVKCCRSW
    

Molecular Weight5947.20 Da

Isoelectric Point (pI)10.22

Net Charge (pH 7.0)7.87

Net Charge (pH 7.4) 7.48

Charge Density (pH 7.0) 0.1458

GRAVY Index0.48

Hydrophobic Moment 0.69

Boman Index0.13

Instability Index47.25

Aliphatic Index 92.04

Aromaticity 0.0926

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2211.29

LogP -18.58

H-bond Donors 86.0

H-bond Acceptors 78.0

Rotatable Bonds 189.0

Heavy Atoms 414.0

Ring Count 12.0

Amide Bonds 54.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0370939 VERIFIED: NO

Provenance & Taxonomy

OrganismBubalus bubalis [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal