Peptide Database

Peptide NameHuman beta defensin 2

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC185H310N56O49S6

DescriptionStandard

        IRNPVTCIRSGAICYPRSCPGSYKHIGVCGVSVIKCCKKP
    

Molecular Weight4295.18 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)6.78

Net Charge (pH 7.4) 6.43

Charge Density (pH 7.0) 0.1695

GRAVY Index0.14

Hydrophobic Moment 0.63

Boman Index0.02

Instability Index55.80

Aliphatic Index 80.25

Aromaticity 0.0500

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1666.22

LogP -18.30

H-bond Donors 65.0

H-bond Acceptors 63.0

Rotatable Bonds 136.0

Heavy Atoms 296.0

Ring Count 7.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232972 VERIFIED: YES

Provenance & Taxonomy

OrganismCercocebus atys [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)