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MYP_093974
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Basic Information
Mastoparan-VT3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C71H132N18O17
Standard
Sequence
INLKAITALAKKLL
Physicochemical Analysis
1509.92 Da
10.30
2.76
2.55
0.1969
0.98
0.60
0.25
-2.84
188.57
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
583.00
-2.32
20.0
20.0
54.0
106.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0321908 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli 37
PMID24012601 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24012601/
RECORD: Rec_0322323 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0322946 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
10 μg/mL
MIC
PMID24012601 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24012601/
RECORD: Rec_0339539 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Enterococcus faecalis ATCC 29212
5 μM
MIC
PaperAntimicrobial peptides from the venom gland of the social wasp Vespa tropica.
RECORD: Rec_0340270 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Gram-positive Staphylococcus aureus ATCC 25923
10 μM
MIC
PaperAntimicrobial peptides from the venom gland of the social wasp Vespa tropica.
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