Peptide Database

Peptide NameRanatuerin-2G

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC142H253N37O40S2

DescriptionStandard

        GLLLDTLKGAAKDIAGIALEKLKCKITGCKP
    

Molecular Weight3182.88 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.0884

GRAVY Index0.32

Hydrophobic Moment 0.56

Boman Index0.13

Instability Index-19.51

Aliphatic Index 126.13

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1236.01

LogP -9.32

H-bond Donors 44.0

H-bond Acceptors 45.0

Rotatable Bonds 113.0

Heavy Atoms 221.0

Ring Count 1.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419342 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates grylio [Animal]

FamilyRanatuerin

Structure & Mods

ConfigLinear peptide with a single intramolecular disulfide-stabilized loop [Linear]

ChiralityGene-encoded natural peptide composed of standard L-amino acids [L]

Disulfide24-29

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus

Activity150.0 μM

MethodMIC

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