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MYP_093960
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Basic Information
Ranatuerin-2G
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
31 amino acids
C142H253N37O40S2
Standard
Sequence
GLLLDTLKGAAKDIAGIALEKLKCKITGCKP
Physicochemical Analysis
3182.88 Da
9.19
2.74
2.50
0.0884
0.32
0.56
0.13
-19.51
126.13
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1236.01
-9.32
44.0
45.0
113.0
221.0
1.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0181023 VERIFIED: NO
Provenance & Taxonomy
Rana grylio [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0181181 VERIFIED: YES
Provenance & Taxonomy
Rana grylio [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
150 μM
MIC
PMID10828493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10828493/
RECORD: Rec_0256746 VERIFIED: YES
Provenance & Taxonomy
Lithobates catesbeianus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0305937 VERIFIED: YES
Provenance & Taxonomy
Rana grylio [Animal]
Ranatuerin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
19 μM
MIC
PMID10828493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10828493/
RECORD: Rec_0329984 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
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