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MYP_093936
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Basic Information
Mastoparan-VT4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C72H132N18O16
Standard
Sequence
INLKAIAPLAKKLL
Physicochemical Analysis
1505.93 Da
10.30
2.76
2.55
0.1969
0.91
0.63
0.26
10.91
188.57
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
553.98
-1.19
18.0
19.0
52.0
106.0
1.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0082777 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperToxicon. 2013 Nov;74:151-7. | http://www.ncbi.nlm.nih.gov/pubmed/24012601 PMID24012601 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24012601/
RECORD: Rec_0083248 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 90028
20 μM
MIC
PaperAntimicrobial peptides from the venom gland of the social wasp Vespa tropica.
RECORD: Rec_0097303 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0100512 VERIFIED: YES
Provenance & Taxonomy
Vespa tropica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 2002
>160 μM
MIC
PaperAntimicrobial peptides from the venom gland of the social wasp Vespa tropica.
RECORD: Rec_0134538 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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