Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length473 amino acids

Chemical FormulaC2326H3732N594O664S21

DescriptionStandard

        MSPCCLLALLALIPLTLAANPGVKVKLTDKGIEYGKQIGMASLQQKLKTIKVPDISGTEKVPHVGKVKYSLTGMTIVNLGLPKSALVLVPGTGVSLAITNAFINLHGNWRVRYFRFIQDRGSFDLAVNGLTITANIAIKSDETGRPMVSTVNCVANVGRASIKFHGGASWLYNLFKSYIDKALRSALQKQICPLVADAITDMNQHLKTFNVLAKVDQYAEIEYSMVTSPTISKSSMEFSLKGEFYNIVKHQEPPFSPTPFSLPPQDNNMLYIGVSSFTPNSAGFVYNNAGALSLYVTDDMIPPSSPIRLNTGTFGVFIPEIAKRFPGMMMKLLVKTVKEPTISLEPNNVTVQASGTVTAYAIQPNTTLSPLFVLNMEGSVSAQLNVTGVKLAGAITLNKIEMTLGTSYVGQFQVQSLDNIFLMVLKVVVIPKVNAHLEKGFPLPSIGKMNLVNTQLQVLKDYMLIGTDVQFTG
    

Molecular Weight51315.46 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)11.99

Net Charge (pH 7.4) 11.31

Charge Density (pH 7.0) 0.0254

GRAVY Index0.20

Hydrophobic Moment 0.70

Boman Index0.18

Instability Index29.84

Aliphatic Index 101.97

Aromaticity 0.0782

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 32110.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0381414 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmo salar [Animal]

FamilyBPI/LBP

Tax ID8030

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria