‹ ›
MYP_093859
← PREVIOUS NEXT → BACK
Basic Information
L-SP40
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Standard
15 amino acids
C90H142N26O23S2
Standard
Sequence
QMRRKVELFTYMRFD
Physicochemical Analysis
2020.38 Da
9.98
1.77
1.56
0.1177
-0.83
0.45
-0.37
69.33
45.33
0.2000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
840.59
-5.27
31.0
27.0
69.0
141.0
3.0
15.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0031062 VERIFIED: YES
Provenance & Taxonomy
Enterovirus 71 [Virus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Ac
Amidation
Bio-Activity Profile
Antiviral
EV-A71 SHA66/97
PMID34715144;22563456 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34715144/
RECORD: Rec_0056555 VERIFIED: YES
Provenance & Taxonomy
Enterovirus 71 [Virus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Ac
Amidation
Bio-Activity Profile
Antiviral
Coxsackievirus A 16
PMID34715144;22563456 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34715144/
RECORD: Rec_0160028 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
SP40
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
EV-A71
93 ± 3 %
Inhibition at 100 μM
Human Serum: 58% remaining after 24 hours, 56% remaining after 48 hours
PaperZarif F, Anasir MI, Koh JX, Chew MF, Poh CL. Stability and antiviral activity of SP40 peptide in human serum. Virus Res. 2021 Oct 2;303:198456 PMID:34314773 https://pubmed.ncbi.nlm.nih.gov/34314773/ PMID34314773 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34314773/
RECORD: Rec_0184877 VERIFIED: YES
Provenance & Taxonomy
Enterovirus 71 [Virus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Ac
Amidation
Bio-Activity Profile
Antiviral
EV-A71 BrCr
PMID34715144;22563456 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34715144/
RECORD: Rec_0194579 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 13.3%, T 20.0%, C 66.7% [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2