‹ ›
MYP_093856
← PREVIOUS NEXT → BACK
Basic Information
Spexin-2
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Standard
18 amino acids
C92H151N29O31
Standard
Sequence
FISDQSRRKDLSDRPLPE
Physicochemical Analysis
2159.36 Da
6.29
-0.23
-0.44
-0.0127
-1.42
0.31
-0.50
103.24
65.00
0.0556
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1005.14
-11.52
35.0
31.0
72.0
152.0
3.0
18.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0036473 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone
Inhibits adrenocortical cell proliferation
RECORD: Rec_0141076 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PMID22038051 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22038051/
RECORD: Rec_0179994 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0235318 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
NPQ
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Myotropic
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for NPQ 53-70 (Homo sapiens): PMID 22038051 PMID22038051 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22038051/