Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length194 amino acids

Chemical FormulaC971H1550N268O265S9

DescriptionStandard

        PKTLPMAHEPMLLLAVTELVANSAAFTYFTAGALRRNFSSDMLPRQFPLQLRTKSMEVFSPELQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELASQPLLCRAQGLPVPQVKRLETLLKFGLWLFGVPRANSKCCPRSVP
    

Molecular Weight21506.92 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)6.29

Net Charge (pH 7.4) 5.94

Charge Density (pH 7.0) 0.0324

GRAVY Index-0.02

Hydrophobic Moment 0.55

Boman Index0.06

Instability Index52.14

Aliphatic Index 94.54

Aromaticity 0.0722

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8396.47

LogP -102.97

H-bond Donors 289.0

H-bond Acceptors 284.0

Rotatable Bonds 683.0

Heavy Atoms 1513.0

Ring Count 41.0

Amide Bonds 209.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249811 VERIFIED: NO

Provenance & Taxonomy

OrganismIlladopsis cleaveri [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria