Peptide Database

Peptide NameSLAY-screened peptide P1534

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC50H68N16O16

DescriptionStandard

        TDHGPNHQPF
    

Molecular Weight1149.17 Da

Isoelectric Point (pI)5.90

Net Charge (pH 7.0)-1.43

Net Charge (pH 7.4) -1.72

Charge Density (pH 7.0) -0.1426

GRAVY Index-1.84

Hydrophobic Moment 0.09

Boman Index-0.15

Instability Index37.15

Aliphatic Index 0.00

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 508.71

LogP -6.42

H-bond Donors 15.0

H-bond Acceptors 17.0

Rotatable Bonds 31.0

Heavy Atoms 82.0

Ring Count 5.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164911 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/