Peptide Database

Peptide NameMra17a

Function Ontology

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Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC136H220N34O45S6

DescriptionStandard

        GSIPCGESCVYIPCISSLLGCSCESKVCYKN
    

Molecular Weight3243.79 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.60

Charge Density (pH 7.0) -0.0096

GRAVY Index0.46

Hydrophobic Moment 0.29

Boman Index0.19

Instability Index32.59

Aliphatic Index 81.61

Aromaticity 0.0645

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1250.31

LogP -15.32

H-bond Donors 49.0

H-bond Acceptors 51.0

Rotatable Bonds 103.0

Heavy Atoms 221.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111664 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Tax ID344147

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

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RECORD: Rec_0354951 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)