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MYP_093800
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Basic Information
CA-ME
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C107H182N26O23
Standard
Sequence
KWKLFKKIGIGAVLKVLTTG
Physicochemical Analysis
2200.75 Da
10.60
4.76
4.54
0.2378
0.52
0.49
0.23
-27.73
131.50
0.1000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
802.57
-2.56
29.0
28.0
77.0
156.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0060585 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Cecropin
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial
NCI-H128
28.6 μM
IC50
PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0062910 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
Magainin
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0109924 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin A-Magainin 2 hybrid peptides
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antibacterial
NCI-H146 (lung cancer)
28.6 μM
IC50
PaperStructure-antitumor and hemolytic activity relationships of synthetic peptides derived from cecropin A-magainin 2 and cecropin A-melittin hybrid peptides | https://pubmed.ncbi.nlm.nih.gov/9352466/ PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0117969 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Cecropin
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial
NCI-H69
32.2 μM
IC50
PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0145458 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus pyogenes
0.1 μM
MIC
PaperPubMed PMID: 1733777 PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
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