Peptide Database

Peptide NameThionin NsW2 (Fragment)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC161H277N53O45S7

DescriptionStandard

        KSCCKNTLGRNCYNTCRFIKKPRKTCAGLCGCKIS
    

Molecular Weight3899.70 Da

Isoelectric Point (pI)9.67

Net Charge (pH 7.0)8.68

Net Charge (pH 7.4) 8.37

Charge Density (pH 7.0) 0.2481

GRAVY Index-0.47

Hydrophobic Moment 0.67

Boman Index-0.25

Instability Index7.72

Aliphatic Index 47.43

Aromaticity 0.0571

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1636.40

LogP -21.50

H-bond Donors 66.0

H-bond Acceptors 61.0

Rotatable Bonds 134.0

Heavy Atoms 266.0

Ring Count 3.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0081694 VERIFIED: NO

Provenance & Taxonomy

OrganismNigella sativa [Plant]

FamilyThionin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function