Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC435H685N121O127S14

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSALPFSEVRELEEAGSNDTPVAAHQEMSMESWMMPSHTRQKRQSHLSLCRYCCKCCKAYNGCGFCCRF
    

Molecular Weight10090.74 Da

Isoelectric Point (pI)7.53

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0076

GRAVY Index0.12

Hydrophobic Moment 0.62

Boman Index0.06

Instability Index52.87

Aliphatic Index 69.44

Aromaticity 0.0889

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3959.56

LogP -40.28

H-bond Donors 148.0

H-bond Acceptors 145.0

Rotatable Bonds 332.0

Heavy Atoms 697.0

Ring Count 15.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239972 VERIFIED: NO

Provenance & Taxonomy

OrganismLabrus bergylta [Bacterium]

FamilyHepcidin

Tax ID56723

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal