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MYP_093742
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Basic Information
E2/1-NH2
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C169H280N46O48S3
Standard
Sequence
SIFSLFKMGAKALGKTLLKQAGKAGAEYAACKATNQC
Physicochemical Analysis
3820.51 Da
9.70
4.44
4.19
0.1199
0.09
0.58
0.10
19.53
74.32
0.0811
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1534.76
-16.40
55.0
56.0
133.0
266.0
3.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0228659 VERIFIED: YES
Provenance & Taxonomy
H. bahuvistara [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus MTCC 9542
3 μM
MIC
PMID31328553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31328553/
RECORD: Rec_0229043 VERIFIED: YES
Provenance & Taxonomy
H. bahuvistara [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli. ATCC 25922
12 μM
MIC
PMID31328553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31328553/
RECORD: Rec_0246847 VERIFIED: YES
Provenance & Taxonomy
H. bahuvistara [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis MTCC 14416
10 μM
MIC
PMID31328553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31328553/
RECORD: Rec_0282456 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human RBCs
15 μM
HC50
PMID31328553 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31328553/
RECORD: Rec_0291739 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Hydrophylax bahuvistara [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
31-37
Bio-Activity Profile
Antimicrobial Anticancer
Escherichia coli ATCC 25922
10 μM
MIC
PaperIdentification and functional characterisation of Esculentin-2 HYba peptides and their C-terminally amidated analogs from the skin secretion of an endemic frog.
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