‹ ›
MYP_093737
← PREVIOUS NEXT → BACK
Basic Information
Loop3
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-Japanese encephalitis virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C32H57N11O15
Standard
Sequence
ATSSANSKA
Physicochemical Analysis
835.86 Da
8.80
0.79
0.61
0.0883
-0.57
0.16
-0.11
30.29
33.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
446.15
-9.30
16.0
16.0
27.0
58.0
0.0
9.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0000154 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Japanese encephalitis virus(JEV):inhibition of viral replication in BHK-21 cells
10±1.4 μM
IC50
PaperPubMed PMID: 22465300 PMID22465300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22465300/
RECORD: Rec_0033510 VERIFIED: YES
Provenance & Taxonomy
Japanese encephalitis virus [Virus]
Virus-derived peptide
11072;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Japanese encephalitis virus (Virus entry); BHK-21
10 μM
Plaque assay
PaperInhibition of Japanese encephalitis virus entry into the cells by the envelope glycoprotein domain III (EDIII) and the loop3 peptide derived from EDIII. | Li C, Zhang LY, Sun MX, Li PP, Huang L, Wei JC, Yao YL, Isahg H, Chen PY, Mao X. | Antiviral Res. 2012 | PMID:22465300 PMID22465300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22465300/
RECORD: Rec_0115181 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 22465300 PMID22465300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22465300/
RECORD: Rec_0203002 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-JEV Replication inhibition
Japanese encephalitis virus(JEV) | BHK-21 cells
10±1.4 μM
IC50
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperInhibition of Japanese encephalitis virus entry into the cells by the envelope glycoprotein domain III (EDIII) and the loop3 peptide derived from EDIII. | Li C, Zhang LY, Sun MX, Li PP, Huang L, Wei JC, Yao YL, Isahg H, Chen PY, Mao X. | Antiviral Res. 2012 May;94(2):179-83. | DOI:10.1016/j.antiviral.2012.03.002 | PMID:22465300 PMID22465300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22465300/
RECORD: Rec_0342380 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 22465300 PMID22465300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22465300/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2