Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length138 amino acids

Chemical FormulaC679H1081N195O185S5

DescriptionStandard

        AQEPMAQEPMVLLALTEFVANSAAFTYFSAGALRRNISGNVLPRRFPLQLNTRSMGVFAPKLQERYPERPMELQLWARQQPLLSCHPHALHGTLLGAAQAFVVLPNATRVPAFLLSIDANVTGKPSIANNRLGASVHL
    

Molecular Weight15096.37 Da

Isoelectric Point (pI)10.37

Net Charge (pH 7.0)5.15

Net Charge (pH 7.4) 4.73

Charge Density (pH 7.0) 0.0373

GRAVY Index0.07

Hydrophobic Moment 0.50

Boman Index0.10

Instability Index55.71

Aliphatic Index 97.68

Aromaticity 0.0725

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6020.31

LogP -57.32

H-bond Donors 204.0

H-bond Acceptors 199.0

Rotatable Bonds 481.0

Heavy Atoms 1064.0

Ring Count 27.0

Amide Bonds 153.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0037984 VERIFIED: NO

Provenance & Taxonomy

OrganismCentropus bengalensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria