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MYP_093613
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Basic Information
[A6]-IsCT (Mutant: W6A; IsCT analog)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C66H113N15O17
Standard
Sequence
ILGKIAEGIKSLF
Physicochemical Analysis
1388.69 Da
8.59
0.76
0.55
0.0585
0.98
0.59
0.39
-2.08
157.69
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
522.09
-1.91
18.0
18.0
49.0
98.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0224338 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus KCTC 1621
64 μM
MIC
PaperPubMed PMID: 15369808 PMID15369808 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15369808/
RECORD: Rec_0295072 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium KCTC 1926
64 μM
MIC
PaperPubMed PMID: 15369808 PMID15369808 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15369808/
RECORD: Rec_0329558 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperPubMed PMID: 15369808 PMID15369808 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15369808/
RECORD: Rec_0336602 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa KCTC 1637
32 μM
MIC
PaperPubMed PMID: 15369808 PMID15369808 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15369808/
RECORD: Rec_0359623 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 69.2%, C 30.8% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Antifungal Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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