Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length284 amino acids

Chemical FormulaC1434H2280N382O385S7

DescriptionStandard

        MKVSTQLDTIAAIDHSLLAPPAFTEEYGDIALKGEIFRVGTYQQRPSALPVVLPVALPMALPVALPLPLPTTPPMAHEPTLLLAVTEFVANSAAFTYFTAGALRRNLSSDMLPRRFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPIITRNRLGGTVRLTGLHITQVASNVGPVEVKRLETLLKFGLWLFGVPRANKWLQAGIPLPLPHGLSLLRPRLSLHQGFVLIATDLQYEP
    

Molecular Weight31256.23 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)4.22

Net Charge (pH 7.4) 3.54

Charge Density (pH 7.0) 0.0149

GRAVY Index0.16

Hydrophobic Moment 0.57

Boman Index0.15

Instability Index51.24

Aliphatic Index 108.20

Aromaticity 0.0739

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 23950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0306934 VERIFIED: NO

Provenance & Taxonomy

OrganismSerinus canaria [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence