MYP_093524
Basic Information
Spiderine-1a (OtTx1a)
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antibiotic activity
Insecticidal/Pest control Insecticidal activity
Toxicity / Safety Cytolysis / cell lysis Cytolytic activity
Toxicity / Safety Cytotoxicity Cytotoxic
Toxicity / Safety Negative safety assay result Non-hemolytic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Toxin
Standard
166 amino acids
C814H1288N216O246S12
Standard
Sequence
MKFALVLLGVCAFYLVNATGDLETELEASELQELQEALDLIGETPLESLEAEELEEARKFKWGKLFSTAKKLYKKGKKLSKNKNFKKALKFGKQLAKNLQAGEEHEPGTPVGNNKCWAIGTTCSDDCDCCPEHHCHCPAGKWLPGLFRCTCQVTESDKVNKCPPAE
Physicochemical Analysis
18421.01 Da
6.13
-2.22
-2.87
-0.0134
-0.48
0.72
-0.04
40.59
72.95
0.0723
19480.00
20105.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
7420.30
-69.75
258.0
260.0
626.0
1288.0
27.0
177.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0417270 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Spiderine; Cationic spiderine subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Cytotoxic Insecticidal Non-hemolytic
Staphylococcus aureus (Gram-positive)
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