Peptide Database

Peptide NameF2L

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC114H174N26O29S2

DescriptionStandard

        MLGMIKNSLFGSVETWPWQVL
    

Molecular Weight2436.89 Da

Isoelectric Point (pI)5.75

Net Charge (pH 7.0)-0.50

Net Charge (pH 7.4) -0.72

Charge Density (pH 7.0) -0.0237

GRAVY Index0.48

Hydrophobic Moment 0.32

Boman Index0.36

Instability Index-6.64

Aliphatic Index 101.90

Aromaticity 0.1429

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 878.30

LogP -3.94

H-bond Donors 30.0

H-bond Acceptors 31.0

Rotatable Bonds 77.0

Heavy Atoms 171.0

Ring Count 6.0

Amide Bonds 22.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0009911 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsAmidation of C-terminal leucine residue; acetylation of N-terminal methionine

Bio-Activity Profile

Function

Receptor agonist Chemotactic Immunomodulatory Signaling peptide

TargetFPR2 (Mouse); FPR3 (Human)

Activity400 nM

MethodEC50