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MYP_093408
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Basic Information
Nisin A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
not Standard
34 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
IXAIXLAXPGAKXGALMGANMKXAXANASIHVXK
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0049811 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
lanthionine-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium smegmatis mc2155
PMID21468208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21468208/
RECORD: Rec_0217457 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
lanthionine-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis H37Ra
PMID21468208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21468208/
RECORD: Rec_0248169 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
lanthionine-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium avium subsp. Hominissuis (CIT05/03)
PMID21468208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21468208/
RECORD: Rec_0323969 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
lanthionine-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium kansasii CIT11/06
PMID21468208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21468208/
RECORD: Rec_0333164 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
lanthionine-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium avium paratuberculosis (ATCC 19698)
PMID21468208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21468208/