Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

—

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC167H269N49O57S2

DescriptionStandard

        KCNTATCVTQRLADFLVRSSNSIGAVYSPTNVGSNTY
    

Molecular Weight3939.35 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0470

GRAVY Index-0.12

Hydrophobic Moment 0.68

Boman Index0.01

Instability Index12.71

Aliphatic Index 71.08

Aromaticity 0.0811

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1747.46

LogP -25.80

H-bond Donors 64.0

H-bond Acceptors 61.0

Rotatable Bonds 125.0

Heavy Atoms 275.0

Ring Count 4.0

Amide Bonds 41.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0206158 VERIFIED: YES

Provenance & Taxonomy

OrganismCorvus cornix [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)